
Ghrelin Receptor (GHSR) Allostery
These last months we explored how the activity of the Ghrelin Receptor (GHSR-1a) can be modulated :

By its ligand Ghrelin
See our paper published in PNAS (2019) on the role of the octanoyl moeity of Ghrelin in its binding to its receptor.

By lipids
See our paper just published in Nature Comm. (2021) in which we predicted and validated binding sites of PIP2 to the intra-cellular side of the GHSR.

And next ...
What about other partners ?