Publications

(3 last years)

2019

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(1)          Neasta, J.; Darcq, E.; Jeanblanc, J.; Carnicella, S.; Ben Hamida, S. GPCR and Alcohol-Related Behaviors in Genetically Modified Mice. Neurother. J. Am. Soc. Exp. Neurother. 2020. https://doi.org/10.1007/s13311-019-00828-y.

(2)          Barrile, F.; M’Kadmi, C.; De Francesco, P. N.; Cabral, A.; García Romero, G.; Mustafá, E. R.; Cantel, S.; Damian, M.; Mary, S.; Denoyelle, S.; et al. Development of a Novel Fluorescent Ligand of Growth Hormone Secretagogue Receptor Based on the N-Terminal Leap2 Region. Mol. Cell. Endocrinol. 2019, 498, 110573. https://doi.org/10.1016/j.mce.2019.110573.

(3)          Cornejo, M. P.; Castrogiovanni, D.; Schiöth, H. B.; Reynaldo, M.; Marie, J.; Fehrentz, J.-A.; Perello, M. Growth Hormone Secretagogue Receptor Signalling Affects High-Fat Intake Independently of Plasma Levels of Ghrelin and LEAP2, in a 4-Day Binge Eating Model. J. Neuroendocrinol. 2019, 31 (10), e12785. https://doi.org/10.1111/jne.12785.

(4)          Howells, O.; Rajendran, N.; Mcintyre, S.; Amini-Asl, S.; Henri, P.; Liu, Y.; Guy, O.; Cass, A. E. G.; Morris, M. C.; Sharma, S. Microneedle Array-Based Platforms for Future Theranostic Applications. Chembiochem Eur. J. Chem. Biol. 2019, 20 (17), 2198–2202. https://doi.org/10.1002/cbic.201900112.

(5)          Ferré, G.; Louet, M.; Saurel, O.; Delort, B.; Czaplicki, G.; M’Kadmi, C.; Damian, M.; Renault, P.; Cantel, S.; Gavara, L.; et al. Structure and Dynamics of G Protein-Coupled Receptor-Bound Ghrelin Reveal the Critical Role of the Octanoyl Chain. Proc. Natl. Acad. Sci. U. S. A. 2019, 116 (35), 17525–17530. https://doi.org/10.1073/pnas.1905105116.

(6)          Henri, P.; Prevel, C.; Pellerano, M.; Lacotte, J.; Stoebner, P. E.; Morris, M. C.; Meunier, L. Psoriatic Epidermis Is Associated with Upregulation of CDK2 and Inhibition of CDK4 Activity. Br. J. Dermatol. 2019. https://doi.org/10.1111/bjd.18178.

(7)          Renault, P.; Louet, M.; Marie, J.; Labesse, G.; Floquet, N. Molecular Dynamics Simulations of the Allosteric Modulation of the Adenosine A2A Receptor by a Mini-G Protein. Sci. Rep. 2019, 9 (1), 5495. https://doi.org/10.1038/s41598-019-41980-x.

(8)          Bayle, M.; Neasta, J.; Dall’Asta, M.; Gautheron, G.; Virsolvy, A.; Quignard, J.-F.; Youl, E.; Magous, R.; Guichou, J.-F.; Crozier, A.; et al. The Ellagitannin Metabolite Urolithin C Is a Glucose-Dependent Regulator of Insulin Secretion through Activation of L-Type Calcium Channels. Br. J. Pharmacol. 2019, 176 (20), 4065–4078. https://doi.org/10.1111/bph.14821.

(9)          Casiraghi, M.; Point, E.; Pozza, A.; Moncoq, K.; Banères, J.-L.; Catoire, L. J. NMR Analysis of GPCR Conformational Landscapes and Dynamics. Mol. Cell. Endocrinol. 2019, 484, 69–77. https://doi.org/10.1016/j.mce.2018.12.019.

(10)       Pellerano, M.; Naud-Martin, D.; Mahuteau-Betzer, F.; Morille, M.; Morris, M. C. Fluorescent Biosensor for Detection of the R248Q Aggregation-Prone Mutant of P53. Chembiochem Eur. J. Chem. Biol. 2019, 20 (4), 605–613. https://doi.org/10.1002/cbic.201800531.

(11)       M’Kadmi, C.; Cabral, A.; Barrile, F.; Giribaldi, J.; Cantel, S.; Damian, M.; Mary, S.; Denoyelle, S.; Dutertre, S.; Péraldi-Roux, S.; et al. N-Terminal Liver-Expressed Antimicrobial Peptide 2 (LEAP2) Region Exhibits Inverse Agonist Activity toward the Ghrelin Receptor. J. Med. Chem. 2019, 62 (2), 965–973. https://doi.org/10.1021/acs.jmedchem.8b01644.

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2018

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(12)       Rebuffat, S. A.; Sidot, E.; Guzman, C.; Azay-Milhau, J.; Jover, B.; Lajoix, A.-D.; Peraldi-Roux, S. Adipose Tissue Derived-Factors Impaired Pancreatic β-Cell Function in Diabetes. Biochim. Biophys. Acta BBA - Mol. Basis Dis. 2018, 1864 (10), 3378–3387. https://doi.org/10.1016/j.bbadis.2018.07.024.

(13)       Rasines-Perea, Z.; Ky, I.; Cros, G.; Crozier, A.; Teissedre, P.-L. Grape Pomace: Antioxidant Activity, Potential Effect Against Hypertension and Metabolites Characterization after Intake. Dis. Basel Switz. 2018, 6 (3). https://doi.org/10.3390/diseases6030060.

(14)       Damian, M.; Pons, V.; Renault, P.; M’Kadmi, C.; Delort, B.; Hartmann, L.; Kaya, A. I.; Louet, M.; Gagne, D.; Ben Haj Salah, K.; et al. GHSR-D2R Heteromerization Modulates Dopamine Signaling through an Effect on G Protein Conformation. Proc. Natl. Acad. Sci. U. S. A. 2018, 115 (17), 4501–4506. https://doi.org/10.1073/pnas.1712725115.

(15)       Podewin, T.; Ast, J.; Broichhagen, J.; Fine, N. H. F.; Nasteska, D.; Leippe, P.; Gailer, M.; Buenaventura, T.; Kanda, N.; Jones, B. J.; et al. Conditional and Reversible Activation of Class A and B G Protein-Coupled Receptors Using Tethered Pharmacology. ACS Cent. Sci. 2018, 4 (2), 166–179. https://doi.org/10.1021/acscentsci.7b00237.

(16)       Shvadchak, V.; Zgheib, S.; Basta, B.; Humbert, N.; Langedijk, J.; Morris, M. C.; Ciaco, S.; Maskri, O.; Darlix, J.-L.; Mauffret, O.; et al. Rationally Designed Peptides as Efficient Inhibitors of Nucleic Acid Chaperone Activity of HIV-1 Nucleocapsid Protein. Biochemistry 2018, 57 (30), 4562–4573. https://doi.org/10.1021/acs.biochem.8b00527.

(17)       Casiraghi, M.; Damian, M.; Lescop, E.; Banères, J.-L.; Catoire, L. J. Illuminating the Energy Landscape of GPCRs: The Key Contribution of Solution-State NMR Associated with Escherichia Coli as an Expression Host. Biochemistry 2018, 57 (16), 2297–2307. https://doi.org/10.1021/acs.biochem.8b00035.

(18)       Nasrallah, C.; Rottier, K.; Marcellin, R.; Compan, V.; Font, J.; Llebaria, A.; Pin, J.-P.; Banères, J.-L.; Lebon, G. Direct Coupling of Detergent Purified Human MGlu5 Receptor to the Heterotrimeric G Proteins Gq and Gs. Sci. Rep. 2018, 8 (1), 4407. https://doi.org/10.1038/s41598-018-22729-4.

(19)       Fernandez, G.; Cabral, A.; Andreoli, M. F.; Labarthe, A.; M’Kadmi, C.; Ramos, J. G.; Marie, J.; Fehrentz, J.-A.; Epelbaum, J.; Tolle, V.; et al. Evidence Supporting a Role for Constitutive Ghrelin Receptor Signaling in Fasting-Induced Hyperphagia in Male Mice. Endocrinology 2018, 159 (2), 1021–1034. https://doi.org/10.1210/en.2017-03101.

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2017

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(20)       Pellerano, M.; Tcherniuk, S.; Perals, C.; Ngoc Van, T. N.; Garcin, E.; Mahuteau-Betzer, F.; Teulade-Fichou, M.-P.; Morris, M. C. Targeting Conformational Activation of CDK2 Kinase. Biotechnol. J. 2017, 12 (8). https://doi.org/10.1002/biot.201600531.

(21)       Martin, C.; Moors, S. L. C.; Danielsen, M.; Betti, C.; Fabris, C.; Sejer Pedersen, D.; Pardon, E.; Peyressatre, M.; Fehér, K.; Martins, J. C.; et al. Rational Design of Nanobody80 Loop Peptidomimetics: Towards Biased Β2 Adrenergic Receptor Ligands. Chem. Weinh. Bergstr. Ger. 2017, 23 (40), 9632–9640. https://doi.org/10.1002/chem.201701321.

(22)       González-Vera, J. A.; Bouzada, D.; Bouclier, C.; Eugenio Vázquez, M.; Morris, M. C. Lanthanide-Based Peptide Biosensor to Monitor CDK4/Cyclin D Kinase Activity. Chem. Commun. Camb. Engl. 2017, 53 (45), 6109–6112. https://doi.org/10.1039/c6cc09948c.

(23)       Fanelli, R.; Floquet, N.; Besserer-Offroy, É.; Delort, B.; Vivancos, M.; Longpré, J.-M.; Renault, P.; Martinez, J.; Sarret, P.; Cavelier, F. Use of Molecular Modeling to Design Selective NTS2 Neurotensin Analogues. J. Med. Chem. 2017. https://doi.org/10.1021/acs.jmedchem.6b01848.

(24)       Delort, B.; Renault, P.; Charlier, L.; Raussin, F.; Martinez, J.; Floquet, N. Coarse-Grained Prediction of Peptide Binding to G-Protein Coupled Receptors. J. Chem. Inf. Model. 2017. https://doi.org/10.1021/acs.jcim.6b00503.

(25)       Neasta, J.; Valmalle, C.; Coyne, A.-C.; Carnazzi, E.; Subra, G.; Galleyrand, J.-C.; Gagne, D.; M’Kadmi, C.; Bernad, N.; Bergé, G.; et al. The Novel Nonapeptide Acein Targets Angiotensin Converting Enzyme in the Brain and Induces Dopamine Release. Br. J. Pharmacol. 2016, 173 (8), 1314–1328. https://doi.org/10.1111/bph.13424.

(26)       Logez, C.; Damian, M.; Legros, C.; Dupré, C.; Guéry, M.; Mary, S.; Wagner, R.; M’Kadmi, C.; Nosjean, O.; Fould, B.; et al. Detergent-Free Isolation of Functional G Protein-Coupled Receptors into Nanometric Lipid Particles. Biochemistry 2016, 55 (1), 38–48. https://doi.org/10.1021/acs.biochem.5b01040.

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